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What is Cannabidiol (CBD) Hemp Oil? How is it processed? 

Is there a difference between CBD oil vs hemp oil? Cannabidiol (CBD) is a popular topic among those who are interested in more holistic approaches to overall well being. It is likely that you’ve heard it connected to topics revolving around tetrahydrocannabinol or THC. But, have you heard of CBD Hemp Oil? How does it differ from cannabis? Do you feel the psychoactive effects? Why use it? And how is it processed compared to other types of CBD? How do we get from a cannabis plant to the CBD you can purchase online and in stores? In this post Panacea Life Sciences will give you the ins and outs of how CBD Hemp Oil is processed and how it may differ from other types. From this, we hope you gain knowledge to further help your journey with CBD.  

First, let us find out what CBD is. 

Further, hemp vs CBD, are they the same? CBD or cannabidiol is a compound in the Cannabis Sativa plant. This is the part that is generally confused with the other compound THC. These are both found in the plant, but the amounts vary. CBD is the non-psychoactive component of the cannabis plant. CBD may assist with a variety of health benefits for one’s overall well being. CBD is found in both Hemp and Cannabis plants, but, Hemp is only defined as Hemp because of the small amount of THC (less than .03%). If a cannabis plant contains more than that percent it is classified as cannabis or marijuana. CBD can be found in many different forms. 

Is CBD legal? 

This is a question that is frequently asked when one often researches CBD. The simple answer is, yes. The 2018 Farm Bill states that hemp is no longer a schedule 1 controlled substance. This bill reaches and is applied to all of the 50 United States. Hemp, being classified (as we stated in the paragraph above) as cannabis sativa that contains less than .03% of THC. So, yes it is legal! 

How is CBD Hemp Oil processed? 

According to this article, there are three types of extraction methods. These include carbon dioxide, steam distillation, or hydrocarbon/natural solvents. 

  • Carbon Dioxide Extraction: Carbon dioxide is used to extract the CBD from the plant by using “supercritical” which, in simple terms means, using both carbon dioxide liquid and gas properties to extract. This is why carbon dioxide extraction is often known as Supercritical Fluid Extraction (SFE). In the beginning of the extraction, two different pressurized chambers are used. One, with the carbon dioxide, while the other contains the hemp plant. Then the chamber filled with carbon dioxide is pumped into the second chamber containing the hemp, where it breaks down the hemp plant and separates it from the CBD oil. The mixture is then pumped into a third chamber where the carbon dioxide is evaporated, leaving the CBD oil unaccompanied. 
  • Steam Distillation: In this process, the steam separates the CBD oil from the plant itself. The hemp is placed in a separate container while a boiler is full of water beneath the hemp. Once boiling, the steam from the water travels upward to extract the CBD oil vapors from the hemp plant. The vapor from the plant is then trapped in a tube and added to oil or water. After this is collected, the oil is extracted from the water to make an oil. This process works well, but requires a lot of the hemp plant and if the steam gets too hot it may damage the CBD oil extract. 
  • Solvent Extraction (Hydrocarbons and Natural Solvents): This process is similar to the Steam Distillation extraction method. But, in this process one would use a type of solvent rather than water. The solvent and CBD oil is combined and then the solvent is extracted leaving the CBD behind. There are two types of solvents used: hydrocarbons and natural solvents. This is the least prefered type of extraction because it has been found to leave unwanted elements after the solvents have been extracted. These elements could be including naphtha, petroleum, butane, or propane for hydrocarbon extraction.

How do I use CBD Hemp Oil? 

Now that we understand the process at which the CBD is extracted and processed, we can ask the questions why and how? The why to this question, why should I use CBD Hemp Oil? It is quite simple. CBD Hemp Oil has been reported by users as a great addition to overall health well being. It has been known to promote a sense of calmness for those who may experience anxiousness. If you have a canine who’s joints aren’t what they used to be, CBD Hemp oil may improve joint mobility. Now, how does one use CBD hemp oil? There are multiple applications of CBD. These include tinctures, vapes, gummies, softgels and topicals. Panacea Life Sciences does not advocate the use of vaping as a method of CBD admission.  

Where can I get CBD Hemp Oil?

You can get CBD Hemp Oil in tincture, gummy, softgel and topical form here at Panacea Life Sciences. Depending on the state in which you live, CBD is also available at local retailers. Be cautious when choosing online retailers and make sure they are reputable. Also make sure that the label clearly shows that the CBD contains less than .03% THC or you may feel effects that were unintended.   

Conclusion

There are multiple ways that CBD Hemp Oil is processed. From Carbon Dioxide extraction to Steam Distillation to Solvent Extraction. Before purchasing CBD it is important to consult a medical professional before taking it. When looking to purchase CBD Hemp Oil do your research! Make sure you are acquiring CBD from a reputable source that uses the method of extraction you deem fit for you. When starting to take CBD Hemp Oil start off with a small amount of milligrams and then increase the dose if you are feeling comfortable. As always, if readers have questions or comments, email us at [email protected] or give us a call at 1 (800) 985-0515.

Sources: 

https://www.cbdoil.org/cbd-extraction-methods/

https://www.agriculture.senate.gov/2018-farm-bill

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Getting to Know More About Cannabidiol (CBD) Gummies

In general, most people have consumed candy in their life. There is a plethora of types of candy, and gummies are just one of them. They come in a variety of shapes and sizes but are recognizable and give us a sense of familiarity.

2013 was the year Charlotte Figi showed all of us the potential health benefits Cannabidiol (CBD may offer to us. At only five years old, this little girl was on her death bed with a condition called Dravet Syndrome. Dravet Syndrome is an extreme condition that made her suffer from frequent and drawn-out epileptic seizures. Figi’s parents drained all the medical pathways attempting to assist their daughter. Then they found a type of cannabis (Hemp) that was low in THC but high in CBD and stopped her harsh seizures in its tracks.

This five-year-old girl’s situation displayed one of the many wondrous benefits of CBD. The studies on cannabinoids are slim pickings because cannabis has not been legalized in many countries. It nearly became hopeless to acquire funding to research the potential medical benefits of cannabis, including CBD clinically. This was all because of the United States 1970 Schedule 1 classification of marijuana that took a sizeable hard hit on the process that could have followed. Nonetheless, a type of evidence that would be titled as anecdotal along with scientific research more than has been seen ever before guides toward multiple of Cannabinoids (including CBD) that may be an option for types of medical issues. Also, in addition to recreational use tied to wellness and health benefits.

One of the most popular and best ways of taking CBD is through gummies among the plethora of choices you may see. We’ll start by talking about CBD and what it is. Then, we’ll explain how it differs from THC.

 

THC and CBD

Cannabidiol, or for short, CBD, is a compound found among many others that are found in cannabis and hemp plants. You have likely heard of THC (Tetrahydrocannabinol), which is the most well-known compound of cannabis because it is known for its psychoactive or “high” feeling that is associated with the use of marijuana and hemp. The compound that is not psychoactive, CBD, does not have the effects that THC does on the brain. Instead, the endocannabinoid system works with CBD and conducts the body functions that maintain the balance in the body.

Generally, CBC is taken from the hemp plant, which is the type of cannabis that consists of organically lower amounts of THC (legally 0.3% or lower). These minuscule amounts of THC have no apparent effects that are deemed psychoactive. The agricultural growth of Hemp in the United States for commercial use is legal in nearly all states. The Agriculture Improvement Act or “Farm Bill” in 2018 took out the Hemp plant from Schedule 1 of the Controlled Substances Act.  

 

Choices, choices: What type of CBD should you take?

Depending on a user’s goal for using CBD, it can be taken in several forms. Luckily, CBD can be taken from marijuana and hemp plants alike. Then, when it is correctly processed, the pureness of most is almost 100% CBD. The extracts or isolates of CBD can be used subsequently in many different ways.

There are options, such as topical ones. Topical options include creams, lotions, serums, and salves that are infused with CBD then are applied on to the skin, and it may help with pain and inflammation for specific areas. An oil type of CBD is available to use by adding it to a number of foods, mixing the oil with drinks or use as-is by putting the oil under the tongue. A trendy and straightforward way of taking CBD is purchasing or even making edible types of CBD. Edible examples include baked goods, gummies, and even hard candy.

 

Important things to understand about CBD Gummies 

Gummies infused with CBD are created similarly to the gummies you would purchase at most stores, but, with a set amount of CBD in every piece. The ingredients generally include gelatin or jelly mix, different sweeteners, and flavoring along with coloring.

Often gummies made with cannabidiol could or could not contain amounts of THC. This depends on the labels put on by the manufacturer. It also depends on the state in which you purchased the CBD gummies. THC is currently only for sale as recreational in 11 of the U.S. as well as Washington D.C. The amount of infused extract that is put into CBD gummies can contain full-spectrum, which means all of the aspects, including all cannabinoids of the hemp plant, are present. The effect, titled as the “Entourage Effect” is then created, which assists in increasing the therapeutic benefits. But a CBD option can also be broad-spectrum, which includes no compounds of THC, or it uses a pure type of CBD isolate.

The amount of CBD in gummies can be lower, but depending on the manufacturer, others may have higher amounts. Be sure to take a look at the bottle’s dosages. A few gummies could even add different ingredients that may help with overall health, for example, adding melatonin for sleeping. Reading the label is of high importance as, as stated before, the amount of CBD in each gummy product may vary.

Naturally, Cannabidiol has a bitter taste; therefore, adding sweetener is quite common. Some manufacturers like to use artificial sweeteners in their gummy products, but others may use corn syrup or a type of natural sweetener that could include beet or cane sugar. There are also a variety of CBD gummies made for vegans. Vegan gummies are made from agar rather than gelatin that is derived from seaweed. When you go to purchase gummies, make sure to read the label if you have a specific type of sweetener you’d prefer.

 

CBD gummies? Why take them? 

Gummies infused with CBD are extremely popular because they are an easy and fun way to ingest CBD. Besides the wellness benefits CBD gummies may give they are an excellent choice for the reasons following:

  •  CBD gummies taste great! CBD naturally has a bitter taste, which could dishearten people from taking it. The flavored gummies hide the bitter taste nicely. Most edible forms of CBD are immersed into the bloodstream quickly, and the effects may be peaked around the two-hour mark after they are ingested.  
  • They are a healthier option contradicting options, for example, of vaping or smoking. And CBD gummies are easy to consume. Those who have a difficult time swallowing pills can use CBD gummies as a possible alternative. Chew and swallow! Just like any other type of gummy. Their discrete size makes them easy to take while working or traveling.
  • CBD gummies that have <0.03% THC have no psychoactive effects, and this means they will not give users a high. Generally, CBD gummies are made from hemp and must have 0.3% of THC amounts or less. A lot of users have explained that there are no “high” or impairment effects; therefore, CBD gummies are safe to drive, work, and do other activities while using.

 

Choices of CBD: What should I look for while purchasing CBD gummies? 

The choices of CBD may be overwhelming and confusing to users. Because of all the information on hemp, cannabis, and the extracts they contain. Use these factors to decide what type of CBD gummies to buy:

Ingredients – Generally, CBD gummies contain sweeteners, among other ingredients that increase the appeal. Paying attention to the ingredients in a CBD gummy is of crucial importance. 

Legal Information – CBD is federally legal in all of the United States since 2018, however there are still a handful of states at the time of this article’s publication where at the state level they still prohibit CBD products. A few CBD gummies may contain THC, which is not legal in all of the states.  

Strength – This is referring to the potency of CBD products. CBD products are measured in milligrams per unit weight. A standard gummy is 5 mg and considered mild, but 10-25 mg is average for most users. 

Source – CBD isolate contains no amount of THC, but it lacks other Cannabinoids that may be beneficial to your body. More wellness benefits come from the use of a broad-spectrum CBD type, so purchase gummies with broad-spectrum hemp infuse. But full-spectrum infused gummies contain the most cannabinoids, so users should be aware that it will likely have a slight level of THC and may not be available for purchase in individual states.

THC amounts – A gummy that is made from pure CBD isolate will not have THC the compound that creates a ‘high.’ If you don’t want any amount of the high, make sure you purchase THC-free gummies. Depending on where you live, you may not be able to buy gummies with THC. 

The FDA does not authorize third-party testing data for CBD gummies and other supplements, so it is essential to be aware that some CBD products may have ingredients of claims that the FDA does not support. Trustworthy, responsible manufacturers usually hire third-party testing and provide the results, so the consumer has the best information available in regards to claims of potency and impurities. You’re more than welcome to check out all of Panacea’s third party testing results here.

 

Typical questions asked about CBD gummies:

Do CBD gummies have side effects? 

he Mayo Clinic states that CBD is safe for use; it may cause mild side effects in some people. These may include dry mouth, diarrhea, reduced appetite, and fatigue. However, if one is new to incorporating CBD into their daily regimen, then by slowly taking smaller serving sizes of CBD and working up to larger ones will help to determine if you may react with any one of the possible many of these symptoms can be caught early if you’re new to using CBD. 

 

Can I give my pet CBD gummies?

All mammals, as well as pets like cats or dogs, also have an Endocannabinoid system that CBD regulates. Gummies are not recommended for pets. With that being said, there are other products, like soft gels, that are easily administered to your pet. You can make a small hole in a soft gel and squeeze the contents inside your pet’s jawline, or perhaps hide it in their food. CBD products may also assist in promoting a sense of calm, joint support, and may help other wellness problems your furry companion could be dealing with. It is most likely you’ll find pet-friendly treats when searching for them. But it is more likely that other forms like oil or CBD-infused treats will be found.

 

What about my anxiety and CBD gummies? Will they help?

Yes. CBD works in the endocannabinoid system in a person’s body. It functions to calm nerves and may help moderate hyperactivity

 

Can I give my child CBD gummies?

Charlotte (the five-year-old from the story above) was given CBD at such a young age because her parents didn’t have many options. Recently, the FDA approved a drug called Epidiolex to treat Dravet syndrome (the one Charlotte had) and another form of harsh epilepsy that began in childhood. This is the first drug comprised of an active ingredient found in hemp and marijuana, CBD, that has been approved by the FDA so far.

You make sure that the CBD comes from a reputable company and does not contain THC. It is an important consideration when deciding what to give to your child. Always consult with your health care professional before purchasing any CBD products for children.

 

Will gummies containing CBD get me high?

Generally, the answer varies depending on the type of CBD gummies you have purchased and consumed. Hemp and cannabis contain over 113 cannabinoids. The ingredients that are active in CBD gummies are Cannabidiol (CBD) and 9-Delta-Tetrahydrocannabinol (THC).

With that being said, THC is the primary Phytocannabinoid known to cause psychoactive effects or the “high” and is the substance that makes marijuana illegal in some states. Hemp in the United States contains less than 0.3% THC, which is not enough to feel any psychoactive effects. CBD was removed from the abusive substances act in 2018 with the passing of the Farm Bill.

 

Now what? 

CBD gummies are a yummy and easy way to consume CBD. They are available in plenty of flavors, may contain added ingredients to benefit your body, and can be carried and eaten anywhere if needed. After reading this, you may now have the confidence and information to purchase CBD gummies and maybe start to experience the health and wellness benefits you’ve read all about.

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Can you overdose on CBD?

CBD products have taken the world by storm, and many people claim that CBD helps them with their chronic pain, anxiety, insomnia and a wide variety of other disorders. However, studies about CBD’s effects are still in their infancy, so it is smart to be a little cautious about it. Still, many people seem to enjoy the effects they receive from CBD, so it is natural to have some questions about it.

One of the major questions people have is whether or not it is possible to overdose on CBD. This is a valid concern, as many drugs that are used to relieve pain can be addictive, leading to a tolerance that requires more and more to get the effect. In unfortunate cases, this can lead to overdoses.

 

What is CBD?

CBD, also known as Cannabidiol, is a chemical that is found in the plant known as Cannabis, or Marijuana. Although CBD is found in Marijuana, it is not one of the ingredients that causes a high, or intoxication. That distinction goes to Tetrahydrocannabinol (THC), which can lead to feelings of euphoria, known as a chemical high. There are other effects from THC as well, such as lethargy, hunger, paranoia and weightlessness.

Though it is closely related to THC, CBD does not cause any of these effects. In fact, some people claim that it doesn’t cause any effect at all, while others say that they get a variety of benefits from it. Instead of getting some sort of mental “high,” users report that they simply experience less pain or anxiety. They might also have an easier time falling asleep and/or staying asleep at night.

The reason that CBD doesn’t cause this high is because it interacts differently with the receptors in your brain than THC does. THC actually attaches itself to these receptors, known as CB1 and CB2 receptors. When you consume THC, you may experience physical changes, such as those in coordination, and mental changes, such as those in your mood.

CBD, on the other hand, seems to encourage your body to use up its natural cannabinoids, so it does not attach to your CB1 and CB2 receptors. This increased cannabinoid production can lead to reduced inflammation and pain but won’t necessarily affect your physical stature or emotional wellbeing.

 

Why do people use CBD?

There are a variety of reasons for people to use CBD. Although the jury is still out on the efficacy of many of its uses, many people swear by the substance to help them with certain conditions.

One of the most common uses for CBD – and the only one that has been approved by the FDA – is to treat epileptic seizures in children. CBD consumption has been proven to reduce or entirely stop seizures in children who suffer from them.

Among other reasons that people use CBD are chronic pain, anxiety, Crohn’s Disease, diabetes, and Alzheimer’s, among others.

 

How is CBD consumed?

There are a variety of ways to consume CBD. One of the most popular methods is through the use of CBD Oil. This can be used in a vape pen, much like nicotine juice. Some people enjoy the different flavors that they can get from these oils and use it as a substitute for smoking. The vapors travel through your lungs and the CBD enters the bloodstream that way. However vaping has been associated with several injuries and some deaths.

For those who don’t like inhaling a vapor, there are other methods as well. CBD foods are highly popular among enthusiasts, and there are many different forms. Gummies are known for their taste and convenience, but they aren’t the only food that can contain CBD. People make pastries, hard candies, and even pastas that contain CBD.

Some people prefer to keep it simple and use CBD capsules or pills. These act just like medicinal pills and don’t require you to spend time consuming them or worrying about flavor.

CBD lotions are good for topical use, like pain management and skin conditions.

Other less traditional ways to consume CBD include sprays, bath salts and crystals.

 

Is CBD addictive?

Many people worry about addictive properties of certain drugs as they fear that they might develop a dependence. Fortunately, when it comes to CBD, there is no evidence to suggest that it is addictive. Some studies actually seem to show that CBD can be used to help those who suffer from addiction to other drugs.

CBD does not cause any sort of high, which means that people won’t be chasing a certain feeling when they consume CBD. Instead, it is intended to reduce pain and inflammation but to keep you relatively level-headed otherwise. There is no “euphoria” that gets harder to achieve every time you take it.

 

What is a drug overdose?

A drug overdose is a dangerous situation when a person consumes too much of any particular drug. If their body can’t handle it or has reached a toxic level of the substance, it will often shut down, leading to serious problems such as heart attack, stroke, seizure or even death.

People can overdose on many different drugs, from easily obtainable items like Tylenol or alcohol to illicit substances such as cocaine and heroin. Mixing different drugs together makes overdose more likely and puts even further strain on the body.

While many people survive overdoses if they receive proper medical attention, it is estimated that over 70,000 deaths occur from overdoses every year. Many of these overdoses were from opioids, which can be dangerous because they are highly addictive and create tolerances that require the patient to take more and more.

 

Is it possible to overdose on CBD?

Despite the fact that CBD is generally considered safe and non-addictive, you may wonder about the potential for overdose. After all, there are many drugs out there that don’t seem dangerous but carry pretty stern warnings about toxicity levels.

Fortunately, there have been no documented cases of anyone overdosing on CBD thus far. Because CBD effects are generally mild and therapeutic rather than intoxicating, you are not going to become “too high” like you might with some other drugs.

You cannot lethally overdose on CBD, but it is still possible to have too much (just like with any other substance). Taking pure CBD in large amounts won’t kill you, but it might lead to drowsiness, diarrhea and dizziness. To avoid this, simply follow the directions on your CBD product. Most studies show that humans can handle up to 1500 milligrams of CBD per day without any issues.

Luckily, there doesn’t seem to be any amount of CBD that can be considered dangerous for human consumption – just levels that may make for some mild discomfort. Because our body naturally produces cannabidiol, we are already used to it and can use it for therapeutic purposes. The most likely scenario if you have more CBD than you are used to is that you will become more tired than usual. For some people, this may be a desired effect.

The most important thing is to start slowly with your CBD consumption to see how much is right for you. If you don’t notice any effects right away, you can slowly add more to your routine and you don’t have to worry about becoming ill or overdosing.

 

What to do if you’ve had too much CBD

While we’ve determined that you cannot overdose on CBD, it is still possible to have a little bit too much, leading to certain consequences. As mentioned, you might suffer from diarrhea or fatigue, but you could also experience nausea, decreased appetite or dry mouth.

None of these side effects are cause for too much concern, but you can take some measures to help alleviate them, as they should be gone within 4-6 hours. Make sure to drink plenty of water, as this will help to flush out your system. You may even be able to reverse the side effects and experience the good effects of CBD.

Eating food can also help with your metabolism, as can taking a walk or simply relaxing. Essentially, you just need to do whatever makes you the most comfortable, and it’s likely that the negative effects will work themselves out. Just make sure not to panic, because it is highly unlikely that there is anything seriously wrong. CBD is such a mild drug that there has never been an overdose, and even most doctors will tell you that it’s perfectly safe to consume.

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10 questions and answers about Cannabidiol (CBD) gummies and candies

These days it feels like CBD is everywhere you look. And right now, CBD gummies and other candies seem to be incredibly popular. Despite this, people still have a lot of questions about these products. So, we gathered up some of the biggest ones in order to answer them and clear up some misconceptions.

 

 

Cannabidiol (CBD) is one of the over 113 Cannabinoid compounds found in Cannabis plants (plants like Marijuana and Hemp). CBD, while gaining in popularity, is often overshadowed by it’s more famous fellow Cannabinoid, Tetrahydrocannabinol (usually know as THC). The two compounds are very different, however. But we will go into more detail about that later. For now, the main thing to know about CBD is that it is found in Cannabis and there is ongoing research into how it may benefit people and their health.

 

 

Now that you have a basic understanding of CBD, you may be wondering why people love it so much. What does it even do? To be honest, that question is still being answered. Research on CBD is preliminary, but it is promising.

What we do know is that CBD interacts with a system of receptors in the body called the endocannabinoid system. These receptors control many cognitive functions in the body. CBD interacts with the receptors and may boost their function. Some of these receptors are the ones that produce dopamine (the chemical involved in motor functions) and serotonin (the chemical that controls moods). As a result, CBD may help boost your productivity or your mood.

There is other research looking into a number of things that CBD may be able to help with. These studies include ones on inflammation, PTSD, skin health and even epilepsy. In fact, there is a newly FDA approved CBD medication designed to help with epilepsy, called Epidiolex. There are some who take CBD daily like they would vitamins. Just as a way to help with their general health and wellness.

 

 

Yes, it is! Most CBD products are legal in all across the United States. This is because a majority of CBD products are derived from Hemp instead of Marijuana. In 2018 the United States Legislature passed the Farm Bill. The Farm Bill is a law that goes under revision every five years (we have an article that goes into more detail about it here). The 2018 version of the bill included a section stating that industrial Hemp with less than 0.3% THC concentration is legal to buy and sell across the country. This was great news for CBD, as Hemp tends to contain much high concentrations of CBD than THC. CBD is also legal in several countries other than the United States.

CBD products that are derived from Marijuana and/or contain more than 0.3% THC are a different story. The legality of those products varies from state to state and is not legal federally. Whether you can find CBD products like that depends on your region’s laws pertaining to medical and recreational Marijuana. If you would like to start using CBD that is nowt from Hemp and/or has more than 0.3% THC, you should familiarize yourself with your state laws on Marijuana.

 

 

No, they will not get you high. As mentioned above, CBD does get conflated with THC often, but they are two different compounds. THC is the component of Cannabis that has a psychoactive effect. It does this by directly binding with the endocannabinoid receptors, CB1 and CB2. This may create a change in appetite, memory and other cognitive functions. However, as discussed above, CBD doesn’t do that. By merely interacting with the receptors, CBD may boost certain cognitive functions, but it does not have the same sort of dulling effect that THC does.

So, if your main hesitation or concern about using CBD lies with the fear of unintentionally getting high, there is no need for worry. While some CBD products do have THC in them, they are legally required to contain less than 0.3%, which is not enough to get most people high.

 

 

When looking into CBD gummies you will likely notice something. Some products that seem to be the same will have different labels. This is because there are three main kinds of CBD oil. They are Full-Spectrum, Broad-Spectrum and CBD Isolate. These titles refer to what else is in the oil with the CBD, because when the compound is extracted it doesn’t come alone.

Full-Spectrum CBD is the most populous of CBD oils. It is the CBD and everything else that comes with it, including terpenes and THC (less than 0.3%, of course). Broad-Spectrum is similar, with one key distinction; it has not THC. It includes terpenes and other compounds, but the THC is completely filtered out. The appeal of these products is that terpenes can add flavor and what is called the “entourage effect.” This is when multiple compounds work together to create a stronger reaction. We have an article that goes into more detail about it here.

The third kind of CBD is CBD Isolate. If you haven’t guessed, CBD Isolate is CBD all by itself. Products with CBD Isolate are nothing but the CBD and its carrier. This is a good option for those who don’t want any THC in their CBD product, or might be allergic to the other compounds.

If you are new to CBD, you may want to start with a CBD Isolate. It will be helpful in figuring out how CBD works for you.

 

 

One common and valid concern that people have when using something like CBD is the potential side effects. CBD does have some, but they are not considered serious. They usually include things like dry mouth, mild nausea, diarrhea and fatigue. However, these side effects are more common in people who take large amounts of CBD frequently. The effects usually fade or completely stop after reducing or stopping the dosage.

That being said, it is still a good idea to talk to consult with a medical professional before you start taking CBD, especially if you are on medication. Some medications do not mix well with the CBD. It may change the effect of the medication or the CBD. All of this goes for any CBD product, including gummies and other candies.

 

 

Because CBD comes from Cannabis plants there are many people who are concerned about how safe CBD use really is. It doesn’t help that in 2018 the Centers for Disease Control (CDC) reported that a string of people were poisoned by consuming a synthetic CBD. This was an unfortunate event but is avoidable.

Right now, the CBD industry is in its infancy and the FDA is still trying to learn how to regulate it. This means that there are those who will try to take advantage of this. The best way to avoid these companies is through research. Before buying from a CBD company read the reviews of their products, find out if they use a third party to test the quality of their CBD and, most importantly, make sure that they are transparent about their process and testing. This is the best way to make sure you are getting a quality product.

All of this being said, CBD gummies should be kept out of reach of children. Most CBD products are designed with adults in mind. A child could easily confuse them for actual candy. While there are no reports of overdosing on CBD, taking too much can cause the side effects discussed above. Plus, there are slightly more serious side effects associated with children using CBD including excessive fatigue. If you want to use CBD for your child, please talk to their pediatrician first.

 

 

There are multitudes of CBD products out there. They range from lotions to tinctures to capsules to drinks. So, why should someone use CBD gummies over anything else? One reason is taste. As we’ve covered, CBD does come from Cannabis, which is known for its distinctive taste and smell. This comes from the terpene compounds in Cannabis. This means that Full-Spectrum and Broad-Spectrum products can have that particular Cannabis flavor. Even CBD Isolate is not free of taste as some users report that it has a bitter taste. Some CBD oils and tinctures have flavoring in them, which may help, but some people may not like the feeling of oil in their mouth. CBD gummies, like any other gummy candy, have flavoring and that pleasant gummy texture. Taking a CBD gummy might be nicer on the taste buds than dropping a drop from a tincture into your mouth.

Another reason why some prefer gummies is control. Sometimes when dropping a tincture into a drink you may accidently get more drops than you meant. With CBD gummies you know exactly how much CBD is in each gummy, making it easy to know how much you are taking.

CBD edibles like gummies also provide a benefit that CBD lotions and other topicals do not. The effects are broader. Topicals tend to stay in the place that you apply them. This is great for people who are using CBD for skin health and inflammation, but if you are looking for a different effect, gummies may be the choice for you.

 

 

It’s true what we were taught in Kindergarten. We are all different. This means that we tend to experience things in different ways. CBD is no exception. Due to a number of factors, some people will experience the effects of CBD much more quickly and much more intensely than others. Some may not experience anything at all from the normal serving size. For these reasons and the level of CBD in the gummy product, the answer to this question varies.

For some people half a gummy will be enough, others may need more. CBD oral products (like gummies) only absorb at a rate between 5-15%, and that rate will vary from person to person. Most manufactures will recommend one gummy a day for most people. The best way to find out what works for you is by starting your servings small. Try one gummy, wait an hour and see how that sits with you. If it’s not enough, try upping your serving size. It’s easy to find what works best for you if you do it in a smart, careful way.

 

 

Yes, they do, but they may work a little differently. As discussed above, gummies are not going to be as localized as a topical. As a result, they are likely to effect you in a more general way. Gummies may also take longer to take effect. One of the fastest ways to get the benefits of CBD is to drop some tincture under your tongue, as it enters your bloodstream more directly. Edibles, like gummies, have to digest before they can start to take effect. Gummies may also last in your system for longer.

As stated before, and should always be remembered, you should talk to your healthcare provider before you start taking CBD. You should start your dosage small and work your way up. It is also important that you store your gummies in a place that a child couldn’t get to them and think they are regular candy.

If you still have questions after reading this article, let us know. Here at Panacea Life Sciences we love hearing from our customers. You can come to use with any CBD related comments, questions or concerns. You can get ahold of one of our team members on our website, or by emailing [email protected].

Reference Links:
Attenuation of early phase inflammation by cannabidiol prevents pain
THE ENDOCANNABINOID SYSTEM PROVIDES AN AVENUE FOR EVIDENCE-BASED TREATMENT DEVELOPMENT FOR PTSD
Cannabidiol exerts sebostatic and antiinflammatory effects
Cannabis, cannabidiol, and epilepsy
Epidiolex
A full breakdown of the 2018 Farm Bill
What is the Entourage Effect
Coagulopathy Associated with Synthetic Cannabinoids Use

Should You Try CBD for Your Pet?

CBD (cannabidiol) for pets? What? Is that safe? Are there real benefits? Will it harm my pet? Will my pet get “high”? How do you give CBD to a pet? Why would my pet need CBD? Pet lovers all over the world want the best for their furry best friend. And why would we not do everything in our power to help them live their best lives? As seen above, there are many questions to ask when it comes to the safety of your most beloved dog, cat, or another fluffy friend. Perhaps this solution may be right for you and may change your loyal companions’ life for the better. In this blog post, we’ll address the information we know and understand to assist you in making the best decision for you and your precious pet.

 

Why? 

This is the first question a pet owner needs to ask themselves. Why should I give CBD to my pet? The reasons may be similar or exactly equivalent to the reason that you may be using CBD or have thought about using CBD. This study provides a plethora of information on CBD pet products and views.  One very interesting statistic is that out of the 632 consumers that had sampled the product, a mere seven percent of pet owners said they felt that the CBD product for their pet did not work as well compared to regular medications or therapies. The other 93% of pet owners felt that the CBD products worked just as well or even better than the standard medications or supplements. They say that the reviews are “make or break”! If you have an animal that you believe may benefit from CBD, keep reading! 

 

Is this legal? 

Yes! CBD is legal in all 50 of the United States since 2018. CBD can be extracted from cannabis or hemp plants. Marijuana, however, is still labeled as a Schedule 1 controlled substance, and you wouldn’t want to give your pet that anyway. The THC (tetrahydrocannabinol) in Marijuana may be harmful to your furry companion. So, let’s stick with the CBD that may help your pet and not harm it. There are no laws that state it is illegal to give your pet CBD in any form. 

 

What is the difference between the THC and CBD compound? 

Before going any further, we’ll explain the difference between THC and CBD, so there is no confusion on whether your pet will be flying high or not. In our titled CBD vs. THC article, it states, “You’ve likely heard of THC, or delta-9-tetrahydrocannabinol, which is the most widely known cannabinoid from the Cannabis plant. The less well-known cannabinoid CBD is a naturally occurring compound in cannabis and Hemp. When researchers first discovered CBD during the 1940s, they did not correctly consider CBD’s benefits and used it because it didn’t deliver an inebriating effect. Instead, they were more keen on researching a new kind of cannabinoid, THC, the compound in cannabis that creates the “high.” The article continues to expand and explain that the THC is the component that is psychoactive, whereas the CBD is not. So, in conclusion, CBD will not get your pet high. Read on, worry-free of high kitties or puppies.

 

How do I give my pet CBD?

There are multiple ways to give CBD to your pet, just like there are multiple ways to give yourself CBD. Humans can attain CBD by using oils, edibles, topicals, etc. Pets can be even pickier than people and may require some fine tuning of their application method. While some less discerning pups will eat a softgel out of their owner’s hand, others will spit it out even after you’ve tried covering it in peanut butter. For picky pups, softgels can also be punctured and the liquid dropped onto food, treats, or even applied directly to the gums if your pup doesn’t mind a little personal contact. Here at Panacea Life, we carry tinctures and softgels for dogs and horses. You can find these products here. As a pet owner, it is important to always ask your veterinarian before giving your pet any type of CBD product. Start with a lower dose and move your way up to a higher dose once you’ve seen the effects it may have on your pet, and if you feel they may need more of an effect. 

 

Woof! CBD for Dogs? 

 Among the hilarious and relentless videos of our favorite dogs running into things a getting stuck places, the internet is chock-full of information on how to help your active pet live  life to the fullest. One of those ways could be assisting them using a holistic method to increase joint health rather than giving prescribed medication. Dogs love treats, right? Right! Our tinctures and soft gels could be added effortlessly to your pup’s favorite wet food, treat or a delicious spoonful of peanut butter. For more information on what type may be best for your dog and what makes a good CBD for dogs, click here. 

 

Movement Disorder Study

Panacea has been conducting an ongoing research study regarding canine health, specifically, age-related movement decreases. Like us, as dogs get older, they tend to have limited joint mobility for a variety of reasons.  In the study, we had pet owners provide their animals two doses of CBD a day and take videos of their pets doing the same movement before and after the CBD was administered such as walking, getting up from a sitting position, getting into a car or climbing stairs We chose certain measurements to be tested, and the six out of the ten measurements ended up being at or above 90%. The survey summary shows that 15.5%-34.9% improvement was visible overall.

 

Meow. CBD for Cats? 

What about your pet that greets you with a “meow” rather than an excited wag of a tail? Why would your furry feline friend need CBD? For the same reasons you would! Did you rescue your cat from a shelter? Perhaps you just want to increase your cat’s quality of life. This article gives a list of why your pet cat could use CBD.. There are many options on how to give your kitty CBD just like there are for your puppy. These options may include oil, soft capsules, and treats. Panacea does not currently carry CBD products for cats, but it is coming soon! Don’t worry. We have not forgotten about your purring pets.

 

Can there be side effects? 

There are side effects to almost everything that you put into your body at high enough concentrations, so the same thing happens to your pets! The general side effects of CBD on pets may be dry mouth, lowered blood pressure, and drowsiness, according to this article. Dogs may also experience  additional negative side effects including, lethargy, vomiting, dribbling urine, and loss of balance at high concentrations, meaning too much has been given to the pet.  Keep in mind that every pet will react differently, just like their human owners and medications. It’s important to consult your veterinarian before and during the use of CBD for your pet. And always make sure you start with a low dose and watch your pet closely to see their reaction. If all goes well, increase the dose if you believe your pet needs it. It’s also important to note that these effects are generally not researched but come from the experiences of pet owners. Research that deals with CBD and pets are still quite slim.

 

Should your pet try CBD? It’s up to you! 

So, the question is, should you try CBD for your pet? We have listed many things above for you to consider. Will your pet benefit from CBD? With the information given above, and if your pet sounds similar to the pets above, it may be likely that your pet could benefit from CBD. Will my pet suffer the psychoactive effects? No! Our products do not contain THC, which gives the “high” effect. Are there negative side effects? Possibly, but consult your vet and watch your pet closely. There are more positive reviews of the effects of CBD and pets than negative ones. Is it legal to give my pet CBD? Yes, CBD is legal in all 50 of the United States. What kind of pet can have CBD? Most research (although slim) and reviews of pet owners is CBD being used for dogs and cats. Again, speak to your veterinarian. If CBD sounds like it could be the right fit for your pet, give it a try! Hopefully, your pet can enjoy the fourth of July fireworks instead of hiding out under the bed.

Reference Links:
CBD as a Therapeutic Management Option for Canine Osteoarthritis

CBD vs. THC

Cannabinoid treats as adjunctive therapy for pets

CBD Oil for Cats

CBD Oil for Dogs: What You Need to Know

CBD for Dogs: Effects

CBD Isolate: When It Was Discovered

If you are interested in Cannabidiol (CBD), it’s always good to know what you are getting yourself into in order to understand it. One way to reach that understanding is by studying CBD’s history. 

 

What even is CBD?

Cannabidiol (CBD) is a compound generally classified as a cannabinoid. Cannabinoids are compounds that found in Cannabis plants (including hemp and marijuana) and there are over 113 of them in any given Cannabis plant.  One of the more famous cannabinoids is tetrahydrocannabinol (THC). There are also a class of compounds called terpenes that have a different set of purposes and effects. Terpenes are most known as the cannabis plant’s master controls for taste and smell. 

 

CBD’s History 

CBD’s individual history is a long road, but doesn’t really start getting chemical until the 1940s. That being said, it’s always good to know some of the basics. 

 

Starting Out Ancient 

Cannabis has been used by humans for a long time whether the purpose was medical or recreational purposes remains a topic of disagreement. The first known recorded case of cannabis being used medicinally dates to around 2727 B.C.E. by Chinese Emperor Cheng Neng. He drank a cannabis-infused tea to help with a number of issues including malaria and gout. Whether the cannabis tea actually helped with these ailments is unclear, but we know that use did not stop there. 

Since that time there have been many people who have used cannabis plants for one purpose or another. For example, hemp was (and still sometimes is) commonly grown and used to make rope and clothing as the fibers in the plant are strong. However, it wasn’t until the 1940s that anyone started to understand the chemical makeup of the plants. 

 

Finding Out What is in Cannabis 

In 1940, a British chemist by the name of Robert S. Cahn discovered a compound in cannabis plants that he called Cannabinol (CBN). This is one of CBD’s fellow cannabinoids but is significantly lesser known. This is probably because it is not as popular for the uses that CBD and THC are known for. Cahn’s discovery showed the world that cannabis contains unique compounds that needed to be understood. 

 

Finally Getting to the CBD 

Two years after Cahn’s discovery another chemist, this time an American, named Roger Adams was able to isolate CBD and THC. He did not quite understand what he had discovered. However, because of the way the two cannabinoids were discovered, they were both pegged as being responsible for the psychoactive effects of cannabis. As a result, CBD was considered something dangerous and to be avoided. 

 

Clearing CBD’s Name 

Not too long after Adams discovered CBD, other researchers started to study CBD. After all, you give a scientist something new, their first impulse is usually to see what it can do. Many of them were testing to see what effect the CBD and other cannabinoids would have. This was difficult, as they did not yet know the structure of the compounds. But the testing went on.  

 

Of these experiments, the best-known is probably those done by Dr. Walter S. Loewe in 1946. He isolated CBD, THC and CBN, then gave the cannabinoids to rabbits and mice. He noted that THC caused the mice to fall into a catatonic state and acted as a stimulant for the rabbits. Meanwhile, CBD did not have any discernable effect on the mice or rabbits. Through this experiment, Loewe was able to tell the scientific world that it was THC that caused psychoactive reactions and not CBD. 

 

Setting the Framework 

In the 1960s there were new technologies that allowed scientists to more easily figure out the structure of a chemical compound. This was important as understanding something’s structure is crucial to understanding its function. Israeli chemist, Dr. Raphael Mechoulam was the first to identify CBD’s structure in 1963. He also went on to discover the structure of THC a year later. Mechoulam’s findings supported Loewe’s conclusions. CBD is not psychoactive, but THC is. 

 

Gaining in Credibility 

As with many scientific discoveries, it took a while for the general public to truly embrace what scientists had been saying. However, in 1978, New Mexico was the first state in the United States to recognize the potential medical uses for cannabis. This state law that was passed did not mention CBD isolate by name, but it is unlikely that the law would have been passed without the research that had been done on the cannabinoid. 

 

Epilepsy and CBD

Midway through 2018, an epilepsy drug known as Epidiolex was approved by the FDA. This was important for CBD as it is the main active ingredient in the medication. This helped add to the credibility of CBD as it is the first CBD medication to be approved by the Food and Drug Administration (FDA). This has led to many people asking the question, “What else can CBD do?” 

 

Legalizing CBD

In December of 2018, the United States Legislature passed a revised version of the Farm Bill. This version of the Farm Bill made industrial hemp growth and hemp products legal across the country. This was an exciting move for those interested in CBD, as CBD is more easily extracted from hemp than from marijuana. This is because hemp has much higher levels of CBD than THC. This meant that CBD could be extracted and sold to the benefit of many people. 

There are still people today who do not fully trust CBD as cannabis has a negative reputation. However, that is changing. As the public understands the compound more fully and as more research is done on CBD’s potential benefits, it has become more accepted. So much of this is thanks to the scientists who laid down the groundwork that allowed for new research to come. It is exciting to watch as this research grows. Afterall, just 80 years ago, we were unsure what CBD even did. Now it is used for everything from maintaining a healthy inflammatory response to skin health. 

We can’t wait to see what another 80 years will bring! 

 

Sources:

https://www.marijuanabreak.com/history-of-cbd

https://www.cbdcentral.com/the-history-of-cbd/

https://ministryofhemp.com/blog/cbd-history/

https://medium.com/cbd-origin/the-history-of-cbd-a-brief-overview-68545c05ccc9

https://www.epidiolex.com/

Panacea Life Sciences Partners with ISU’s College of Veterinary Medicine to Research Effects of CBD on Animals

GOLDEN , COLORADO, UNITED STATES, March 3, 2020 — Panacea Life Sciences is funding an innovative research project with Iowa State University’s College of Veterinary Medicine, Diagnostic and Production Animal Medicine to investigate the analgesic effects of CBD to control pain in dairy cattle. This study will measure the pharmacokinetics of CBD in this species as well as the ability of cannabidiol to provide analgesia in the dehorning operation common in the dairy industry.

Pain control associated with management procedures (dehorning and castration) as well as lameness in dairy cattle is a significant welfare concern of US dairy farms. In the US, there are currently no products labeled for pain control for bovine in this industry, except for transdermal flunixin. However, this product is only labeled for pain control associated with interdigital pododermatitis (foot rot) in beef and non-lactating dairy cattle. Veterinarians often use non-steroidal anti-inflammatory drugs (NSAIDs) such as flunixin meglumine or meloxicam for pain control, but there is limited data supporting the use of one over the other when it comes to pain management associated with dehorning and castration.

The clinical study plans to approach this work in four general phases:
– Validate a Liquid Chromatography (LC)-mass spectrometry (MS) analytical assay for the detection of CBD in bovine plasma using procedures like those described by the FDA. (Bioanalytical Method Validation – Guidance for Industry – 2018). LC/MS, above, is a method for detecting specific analytes, in this case, CBD, to get down to the parts per billion that you need to quantify blood CBD levels.
– Conduct a pharmacokinetic study of CBD in pre-ruminant dairy calves.
– Conduct a pain mitigation study using a hot iron dehorning model in young calves to determine the analgesic properties of CBD at various CBD dosages to determine an optimal dosage regimen.
– Using the dosing regimen(s) determined, conduct a comparison study between CBD and commonly used NSAIDs for the control of pain associated with dehorning.

The overall hypothesis of this work is that the analgesic properties of CBD would be superior to that of NSAIDs.

James Baumgartner Ph.D., the director of this research for Panacea Life Sciences, comments, “This represents Panacea’s dedication to better understand the science of cannabinoids. We are extremely pleased and excited to work with Iowa State University and Patrick Gorden to explore cannabidiol effects in food and fiber animals, such as dairy cattle, beef cattle, pigs, chickens, and goats. Our hope is that industrial hemp products will provide a necessary, organic alternative for these animals’ unmet needs.”

Leading this investigation is ISU’s Patrick J. Gorden, DVM, Ph.D., DABVP, DACVCP Associate Professor, who is assisted by Rochelle Warner, DVM, MS, Kristen Hayman, DVM, and two Ph.D. students.

Dr. Baumgartner adds, “We are continuing to bring essential information to our customers and partners about the health benefits of cannabidiol. As Panacea continues to grow and evolve, partnerships like the one with ISU’s College of Veterinary Medicine will play a crucial role in the endorsement of CBD’s many capabilities.”

About Panacea Life Sciences, Inc.

Panacea Life Sciences, a woman-owned and woman-led company, is dedicated to developing and producing the highest-quality, medically-relevant hemp-derived cannabinoid products for consumers and pets from our 51,000 square foot, state-of-the-art extraction, processing, manufacturing, and fulfillment center located in Golden, Colorado. Panacea operates in every segment of the CBD product value chain, from cultivation to finished goods, with stringent testing protocols employed at every stage of the supply chain from seed-to-sale. Panacea products can be purchased online at https://panacealife.com. For more information about Panacea Life Science’s history and management team visit https://panacealife.com/about/.

Panacea’s founder, owner, and CEO, Leslie Buttorff, recently earned the prestigious 2019 Champion Award at Iowa State University’s Ivy Women in Business Awards. The awards honor women in business and those who work to inspire and advance the careers of women.

Nicholas J. Cavarra
Panacea Life Sciences, Inc.
+1 720-201-7313
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On the Topic of CBD Topicals

Cannabidiol (CBD) is in everything these days. It’s in food, drinks, makeup, bath products, and even dog treats. So, it’s likely not surprising to learn that you can buy lotions, creams and other topicals that have it. But this does raise some questions. For example, why would I want to use lotions? Or even more importantly, what is CBD?

Let’s take the next few minutes to answer those questions, shall we?

Defining CBD

CBD, known in more formal circles as Cannabidiol, is one of over 113 compounds found in Cannabis plants. Marijuana and Hemp are the most well-known members of this plant family. As a result, CBD is commonly conflated with another Cannabis compound, Tetrahydrocannabinol (THC). However, it is important to know that THC and CBD are very different.

THC is probably better known than CBD for one primary reason; it is the compound in Cannabis that is psychoactive. In other words, it creates the “high” that is so often associated with Cannabis. CBD, on the other hand, does not have this effect. Most CBD users report that they feel a calm. That CBD helps them relax but has no adverse effect on their cognitive capabilities. 

CBD and THC also help create the difference between hemp and marijuana. When someone mentions Cannabis, many people think of people getting high. However, that is not Cannabis in general. That is an association that should be more with marijuana than hemp. This is because marijuana has high levels of THC and average levels of CBD. Hemp on the other hand, is low in THC and contains much higher levels of CBD. This is why industrial hemp and products derived from it (including CBD products) have been legalized across the United States.

 

What is the benefit of CBD topicals?

There are a few reasons why people use CBD topicals. The main ones are to combat inflammation and as a boost to skin health. While the research on what CBD can do to benefit those things is still preliminary, it is promising.

Inflammation is something that can cause a lot of problems, for a lot of people. It can lead to discomfort and even pain. So, dealing with it can be difficult. One study published in 2013 found that CBD helps act as an anti-inflammatory in mice. This is just one study of many out there looking at the anti-inflammatory effects of CBD. Using topicals for this purpose may be more effective as the topicals tend to keep their effects in the area that you apply them. That means that it will be more concentrated in places where you are feeling the most inflammation.

Skincare is important for everyone. If you are struggling with acne, many products can be discouraging as they can mix with the oils on your skin and exacerbate the issue. CBD may be able to help with this. As this Healthline article lays out, CBD may help reduce the body’s production of sebum, the oil that while protecting our skin, can also clog up our pores. This means that your odds of experiencing breakout may drop when using CBD.

If you are taking medications for either of these issues, be sure to talk to your doctor before stopping or changing the way you take your medications.

 

Top 5 things to know before using CBD topicals

Many CBD manufactures sell CBD topicals that are specifically designed to help with these issues. But before you run off to buy them, there are a few things you should bear in mind:

  1. There are different kinds of CBD. There are three of them to be exact. They are full-spectrum, broad-spectrum and CBD isolate. These names indicate how many other things there are in the product other than CBD. Full-spectrum has all of the other compounds that come with the CBD, including THC (though legally it cannot be more that 0.3% THC). Broad-spectrum has everything except the THC. The idea behind the first two is to take advantage of the “entourage effect”, which is when several different compounds build on each other to do more than any single compound can alone. (We go into more detail about it here, if you are curious). CBD isolate is just CBD. Nothing else, just pure CBD in the topical formulation. 
  2. Everyone experiences CBD differently. People are different, so it follows that CBD may work differently for some people than others. You may find that more or less of the topical will work best for you. Be smart, try small amounts at first, and experiment with the dosage by adding a bit more at a time.
  3. Find a trustworthy source. The CBD industry is still rather new. As a result, it is not quite as mature or regulated as it will likely be in the future. However, this does mean that there are those who take advantage of the current, lax rules. When looking for a good CBD product, be sure to research the company you buy it from. Check to see if they use third-party testing to ensure the quality of their products.
  4. Talk to a medical professional. This is just good advice for any major change you make to your lifestyle. There are some medications that may not interact well with CBD. If you’re taking topicals, this may not be as big of an issue as it might be with oral CBD. However, it is still a good idea to talk with your doctor to be on the safe side.
  5. There are potential side effects. However, these side effects generally are not serious. And they are mainly reported by those who ingest high quantities of CBD consistently. These side effects include things like mild nausea, dry mouth, gastrointestinal upset, and fatigue. If you start to experience these, you should either stop using the CBD product or reduce your dosage.

 

CBD topicals are a great way to localize your CBD usage, keeping the effects right where you want them. Feel free to explore and try a few different kinds to find the one that works best for you.

 

Sources:

https://www.healthline.com/health/skin-disorders/cbd-for-acne#for-acne-scars

https://health.usnews.com/wellness/articles/do-topical-cbd-products-work

https://www.ncbi.nlm.nih.gov/pubmed/22850623

https://www.self.com/story/cbd-for-pain-topical

How does Cannabidiol (CBD) affect your dog?

How does Cannabidiol (CBD) affect your dog?  Cannabidiol’s (CBD) effects on and benefits for human health has to lead to an increase in research over the last few years, leading to greater understanding. What has only just started to be looked at, is what CBD does for dogs, or if they can even take it. To add to the confusion, the information available on the internet about dogs and CBD can vary depending on where you look, making it difficult to know what’s right.

Of course, as dogs are man’s best friend, you want the best for your dear pet. Here at Panacea Life, we understand that and are doing our best to research how CBD may be able to help dogs. We even conducted a study looking at CBD’s effect on improving movement and mobility. 

The goal of this article is to look further into questions and clear up possible misconceptions surrounding CBD and dogs so that you can fully understand it before trying it out on your dog. It would be best if you came away from it feeling confident in your knowledge of CBD so you can be comfortable enough to give it to your dog.

 

Tell Me More About What CBD Is

Cannabidiol (CBD) is one of many different compounds that are found in plants from the Cannabis family. This family includes marijuana and hemp. CBD is considered to be the more medicinal side of Cannabis.

CBD, when taken by humans, comes in many different forms. They can be anything from lotions to candy to drinks to pills. Dog products range from treats, soft gels, or oils to be mixed in with food or rubbed onto your dog’s skin.

I’m Concerned CBD Will Get My Dog High

Many dog owners may hesitate to give their pet CBD because they worry that it will have a psychoactive effect on their dog. However, they don’t have to fret. CBD, unlike it’s more famous cousin Tetrahydrocannabinol (THC), does not have any psychoactive effects on people or dogs. That is to say, THC gets you high, but CBD does not.

 

How Legal is CBD?

As of December 2018, the Farm Bill made CBD extracted from hemp with less than 0.3% THC legal to buy and sell in most states. However, marijuana and anything extracted from it (including CBD) is still a controlled substance and is therefore federally still illegal.

 

Hemp with THC Being Given to Animals

Unfortunately, there are many stories and videos out there of dogs that were accidentally given large doses of THC. It makes them confused or even frenzied. It is something that you should avoid for your dog. Veterinarians say that your dog should not consume any THC.

While the consensus on how THC affects your dog is pretty clear cut, researchers are still trying to understand all of the benefits of CBD for canine health. There has been an increase in studies looking at CBD in dogs, but these studies are still preliminary and need more time. However, many veterinarians report that CBD appears to have mainly positive effects. 

As this research is still in progress, it is essential to be careful in giving your dog CBD. Dogs may experience some side effects from CBD that are not severe, mainly causing fatigue and gastrointestinal upset. Starting your dog’s CBD doses small may help avoid this.

How might CBD help my dog?

Humans often use CBD to help with things like joint support, promote calm feelings, and even sense of restfulness. For dogs, it may have similar benefits. Using CBD to help calm down a dog with stress caused by noise or separation anxiety has become increasingly popular. This is not surprising as many human CBD users report a feeling of calm caused by CBD.

Other dog owners use CBD to help their dogs with poor joint health. As discussed above, at Panacea Life, we conducted a study that utilized CBD with a focus group of dogs with osteoarthritis. The owners of our test group observed an improvement in mobility for their pets. Please feel free to look over the study in further detail for more! 

How do I give my dog CBD?

CBD for animals is found in many different forms, including gummies, powders, and treats. It may be possible even to find a CBD chew toy. However, the easiest way may be to use CBD oils or tinctures. It tends to be the purest form of CBD, and soft gels are often made using these.

 

CBD may taste slightly bitter when it is extracted from Cannabis. As a result, it is likely your dog won’t be very keen to open wide. So, you’ll probably have to get a little creative. At Panacea Life, our dog products all use fish oil to make the taste more enjoyable to animals. But if you still need a suggestion or two on good ways to administer any CBD product of y our choice, here are a few suggestions:

 

If you have any questions, comments, or concerns, you can contact a member of the Panacea team either on our website or by emailing [email protected].

Reference Links:
CBD as a Therapeutic Management Option for Canine Osteoarthritis
The CBD Oil Debate: Is It Safe For Your Dog?

CBD Candy Sweet Tooth

It seems like everything these days has Cannabidiol (CBD) in it.

Recently, it has gone from being a corner product that not many people talked about, to be found in the mainstream. People all over the world have started to use CBD as part of their daily routines, raking in the benefits.

It seems like every part of the health and beauty industries have started using CBD in their products. For example, the beauty industry has started introducing CBD into facial oils, lip glosses, and even mascara, all to the joy of their customers. Healthcare within the sports industry has joined in as well.

Social media influencers on Instagram and other platforms are fans of CBD-infused products due to the number of positive posts. It feels like no matter where you look on social media, CBD, and other Cannabis products are anywhere and everywhere.

While there are many different kinds of CBD products out there, at Panacea Life, we’re particularly excited about edible products. We have noticed that people seem to especially like CBD candies as a method to add CBD to their daily regimen.  Candies and sweet edibles have all but taken over the CBD world in the last year. Between the taste, benefits, and price, it’s not hard to guess why.

If you are new to CBD and CBD gummies, this is the blog post for you, as we will be taking an in-depth look at gummies and what you should know. If you already know all you need to about CBD gummies and think you are ready to try some, check out the products we have in stock here, like our Cherry Bomb CBD Gummies, for example.

 

What is CBD?

It’s probably a good idea we lay out some basics and answer some questions before we get to the main event. What is CBD? After all, there are some people who will say that it will get you high or cause harm.

Cannabidiol (CBD) is just one of the over 113 cannabinoids found in plants that are part of the Cannabis family. Despite popular misconception, many sources will confirm that CBD has no psychoactive effect, meaning it does not create the “high” that is normally associated with Cannabis. 

One of the more common ways to find CBD is in soft gels. Anyone who has been to a health store in the last couple of years has probably seen a few different kinds of this product. CBD oil soft gels are created by extracting the compound directly from a Cannabis plant and mixing it with a carrier oil.

 

What do people use CBD for?

People who are new to or have never used CBD often have a hard time understanding why so many people included CBD in their daily health and wellness routines. Attitudes may be changed as recent research involving CBD has been pointing to its potential to help with a number of things, including general wellbeing.

There are those who struggle with things like Multiple Sclerosis or arthritis that have reported that daily CBD use has helped create some relief within their daily activities. Sativex, a CBD and Tetrahydrocannabinol (THC) mixture, is an approved drug to treat muscle spasms in MS patients.  MS patients are turning to over the counter CBD preparations instead of Sativex due to cost and to achieve the benefits of CBD without the psychoactive effect of THC. The Journal of Pain Research published a study backing this up in 2018.

People have also started using CBD to help with skin conditions. It is commonly found in many skincare and beauty products –at  Panacea Life we carry a face crème that you can view here. It is possible to find products infused with CBD like lotions, cream, and moisturizers, all with the intention to provide the user with beautiful skin.

Many people who use CBD report that it creates a calming effect, another major benefit of the compound as that may help make mental wellbeing. It seems likely, according to Healthline, that CBD may end up factoring into treatment for things like anxiety, stress, and even insomnia as there has been rising research on the subject.

As you can see, there are a lot of potential benefits that may be reaped when using CBD and CBD infused products. But, like any health-related product, you should consider all parts of it in order to figure out what will work best for you, so let’s take a look at those aspects.

 

What can have CBD in it?

It really is exciting to see the amount of innovation going on in the CBD and Cannabis industries when it comes to products. Companies are always coming out with new, different, and compelling products, some of which include:

Obviously, this list is not all of the possibilities where CBD can be found, and it is just a sample of some of the more unique and different forms of CBD coming to the forefront. All of us here at Panacea Life are so excited to be part of such a new, different and innovative industry with all kinds of unique and creative minds at work, and we can’t wait to see where it will go in coming years. 

 

The big question: what even are “CBD gummies and candies”?

It’s time for the main event, the section we’ve all been waiting for: CBD candy. Recently, this branch of CBD product has gotten some major traction and, as a result, popularity.

So, let’s discuss and define what they are.

We’ve been throwing around the terms “CBD gummy and candy” a lot, but that’s a pretty broad term. It’s usually referring to any kind of candy that has CBD in it. This could include suckers, hard candies, chocolate, and of course, gummies, as long as they have had CBD infused into it. There are so many different kinds of styles and flavors of candy, and some are even halal and vegan-friendly.

Because they are so yummy and come in so many different varieties, CBD candy has and will likely continue to rise in popularity. This has led to many mainstream brands and media outlets becoming more aware of what CBD actually is and all of its potential benefits (that we know of, anyway).

Because of the shift into mainstream consumption, the misconceptions that created a negative stigma for CBD have started to disappear.  Consumers are starting to understand CBD and products made with it better. There are still those who have a negative connotation of CBD and its products because of its connection with Cannabis and, as a result, drug use, but they appear to be in the minority as people learn more about CBD.

Overall, CBD edibles, including candy and gummies, are very popular at the moment and are worth looking into if you are curious about CBD.

 

What’s so great about CBD candy?

As we’ve discussed above, CBD candy and gummies are increasing in popularity.

One of the more obvious reasons is because they taste great. Other products, like oils or tinctures, may be harder to swallow since they tend to have the bitter taste that is common in Cannabis-related products. But candies are made to be delicious, with sweet tastes and nice textures mixed in.

As we discussed above, CBD candies seem like a good way to help people relax and reach a state of calm. CBD oil has a link with anxiety regulation that applies to candy as much as it does with other products. Of course, that does depend on the strength of the particular product as that may change its potency and effect. 

CBD candies may be a yummy way for those who are already used to using CBD to change up their routine a little. If you always use a CBD tincture, you might want to give the candy a shot in order the shake things up. It might be the sweet little jolt of change you’ve been looking for in your life. 

To wrap this section up- CBD candies are yummy, good for you, and an interesting introduction into the world of CBD products. Who wouldn’t like that?

 

What’s the catch?

Just like anything else, you may take for your health, you should consider the potential downsides to CBD candy. While CBD and related products don’t have any serious or major side effects, there are some negative things that all users should know. 

One of these is that some synthetic CBD products could potentially be harmful. A  report from 2018 published by the Center for Disease Control talks about a number of cases of poisoning associated with artificial CBD products that were very impure.

This illustrates why it is so important to be sure that you are getting your CBD products from reputable sources like Panacea Life. 

You should also consider what medications you are taking before you start taking any CBD products. CBD may not interact with some medications well, causing the intended effect of the medications to lessen or, in combination with the medication, cause unwanted side effects. If you take any prescription medications and want to start taking CBD, be sure to talk to a medical professional.

While the side effects associated with CBD are minimal, they do still exist. The Mayo Clinic lays out exactly what they are. Among the list, there is diarrhea, dry mouth, fatigue and loss of appetite. It is worth noting that most of these side effects mainly happen to those who take very large amounts of CBD consistently. The best way to avoid them is by limiting your dosage, keeping it small at first and building it up if you respond to it well.

You should also be aware that research on CBD and its long-term effects is still preliminary and ongoing. Most of the studies are exciting and promising, but there is still a lot of work ahead.

In general, the negative effects of CBD are minimal and are easily lessened or even stopped by being smart and doing some research. You should always look into the company that you buy your products from and be sure that CBD will work well with your medication. You should also be sure that the CBD products that you use are compliant with your local state laws.

 

What does all of this mean?

There are many reasons why there has been an upswing in popularity for CBD candies. They are an easy and delicious way to get the benefits that CBD has to offer.

No matter how experienced you may be with CBD, candies are a great option. Just be sure that you do research and buy from a trustworthy source to really get the benefits you’re after. 

 

What can Panacea Life do for me?

At Panacea Life we have a wide variety of CBD products. We carry lotions, oils, tinctures, capsules and, of course, gummies. Feel free to take a look at our full website here.

If you have any questions, comments or concerns, you can get ahold of one of our team members through our website or by emailing [email protected] today.

Can CBD help ADHD?

Attention deficit Hyperactivity Disorder (ADHD) is a label that seems to be thrown around a lot. Most often, it gets pinned on kids and teenage boys who can’t seem to sit still. It will even be used by people to describe being distracted. Those with ADHD know that it’s more than just squirming in your seat and getting lost in thought. They know better than anyone how trying this condition may be.

People with the disorder have likely tried several different ways to lessen symptoms with medication is one of the most common forms of treatment. People are exploring approaches other than prescribed medication to alleviate symptoms of ADHD.  Recent studies suggest that Cannabidiol (CBD) oil could be a potential treatment for this affliction.

The use of CBD may be an encouraging thought for some and there are others who may hesitate. This is understandable as the idea of CBD being used as in ADHD treatment leads to several questions. It is important that those questions are addressed and answered, starting with the basics.

 

What is ADHD?

ADHD is a common mental disorder that despite popular belief, affects adults and children alike. As the acronym suggests, ADHD  is usually associated with inattention and hyperactivity. 

According to recent research, ADHD impacts about 4.4% of adults and 9.4% of children in the United States. Symptoms usually start to emerge between ages three to six. Most cases are not even caught until they are children who are seven years old. Diagnoses as more medical professionals recognize the disorders are increasing annually. In the last eight years, diagnoses of ADHD are up 42%. Males are more likely to be diagnosed with it than females. This is partially due to the fact that the symptoms tend to be different in women than men.

Common male symptoms include hyperactivity, lack of focus, and impulsiveness. For females, the symptoms are not as outwardly obvious. They generally include low self-esteem, anxiety, verbal aggression, and withdrawing socially. When they are younger, boys with ADHD are generally labeled as hyper, while girls get called spacey. Despite the differences, these symptoms may often make things like school and work difficult for those who wrestle with them.

While it is something that is looked for more in children, adults may struggle with ADHD too. In fact, recent years have seen a rise in the number of adults (especially women) who have been diagnosed.

How is it so prevalent?

Most studies suggest that ADHD is usually related to the patient’s genetics. Three out of four people with ADHD have a relative who has it as well. However, there is also evidence that things like brain damage, premature birth, and complications with pregnancy (complications, including smoking and severe stress during pregnancy) may also cause ADHD.

It is common for those with ADHD to be on medication to help regulate the symptoms. However, not everyone may take medication. Allergies and negative side effects may make it unpleasant or impossible to take. Plus, in some cases, these traditional routes may not sufficiently address symptoms which have created a need for alternative approaches to help people cope with the disorder.

 

What is CBD?

Most people have probably heard of CBD. CBD oil has had a jump in popularity over the last few years, partly because of its legalization across the United States and in several other countries around the world, but largely due to the number of positive health benefits reported with CBD usage. Be that as it may, many people still are not sure what it is and may confuse it with another Cannabis compound.

CBD is a compound extracted from plants that are members of the Cannabis family, plants like Marijuana and Hemp. CBD is often associated with and confused with tetrahydrocannabinol (THC). The confusion is understandable. THC is much more well-known than CBD. Despite being found in the same family of plants, they have very different biological effects.

One difference between CBD and THC is that while both compounds are found in Marijuana and Hemp, they are found at different levels. Marijuana is richer in concentrations of THC, which is why it is more associated with the high generally connected with Cannabis. Hemp, meanwhile, is much higher in CBD concentrations. Hemp is used more often by CBD manufactures to extract the compound.

THC creates the high that is most often affiliated with Cannabis. It does this by binding with the two main human Cannabinoid receptors, called CB-1 and CB-2, briefly changing the brain’s chemistry. CBD, on the other hand, does not directly bind with these receptors. This means that CBD does not produce the same high as THC. 

Instead of interacting with Cannabinoid receptors, CBD may activate several different receptors in the body, including boosting those that produce serotonin (possibly making you feel more positive) and dopamine (which affects your cognitive functions, potentially helping with motivation). CBD oil is often used to promote a sense of calm, to rare forms of epilepsy, and for promoting general well being.  Since industrial hemp’s legalization, we are still trying to understand what exactly CBD may do and how it may help people. 

 

How may CBD help with ADHD?

There has been a recent upswing in the number of studies looking at the impact CBD may have on ADHD. Generally, there need to be several studies showing the same results before an assertion like this may be treated as fact. Many studies that are being done are focusing primarily on THC or Cannabis in general. There is still work and research that needs to be done on CBD specifically. 

One 2012 study published in the Journal of Psychopharmacology looked at the effect CBD had on the hyperactivity of rats. This investigation found a significant drop in the hyperactivity of the rats that were given the CBD. Not only did it calm the rats, but they also concluded that there was no obvious negative impact on the creatures’ attention spans.

Even though studies looking at CBD and ADHD are lacking, there are plenty on the effects of CBD on one of ADHD’s biggest symptoms: anxiety. In 2011, the Nature Publishing Group published a study that showed that CBD could possibly help reduce anxiety. This could be a benefit for many of those who wrestle with ADHD induced anxiety. It could especially help women, in whom anxiety is a very common symptom.

Despite the lack of human clinical studies for direct effects of CBD on ADHD, there is a considerable number of personal testaments from people with ADHD, claiming that CBD oil and Cannabis have helped with their symptoms. A study published in 2016 by PLOS ONE found that Cannabis was commonly recommended to those struggling with ADHD by other patients.

 

The best ways to take CBD for ADHD

CBD is easy to personalize in that it may be taken in several different forms, derived from several different strains, and is available in several different concentrations. Finding what works best for you will take some experimentation. It is smart to ease into starting a CBD regimen. All people are unique. Two different people may have completely different reactions to the same strain and concentration. To avoid having unwanted side effects, start your dosage with simple strains, in low concentration. If you do not have any adverse effects, you may slowly adjust up the amount, maybe even try a new strain.

The best way to keep track of and control how much CBD you’re taking is by using oral products. There are a few different ways to take CBD orally. Capsules, tablets, tinctures, and gummy edibles are popular and easy (and, in some cases, yummy). You may also use CBD through lotions and balms. But these are often used as a treatment for inflammation or for skincare, but they are not effective for addressing ADHD. For treatments of things like ADHD and anxiety, taking CBD orally is recommended.

Despite ADHD being so prevalent in children and teenagers, CBD is not generally recommended for children and those under 18. There is not enough information about what potential effects it may have on a developing mind. If it seems like CBD is something that could help with your child’s ADHD, consult with your pediatrician about it.

While some of these studies regarding CBD and ADHD are promising, they are not conclusive. There is still plenty of research to be done on the mental benefits of CBD. Be sure to talk to your doctor before trying CBD as an ADHD treatment. If you are taking medication to help with your ADHD, talk to your doctor.

With an increased focus on how CBD works with ADHD, research seems to suggest that CBD may be a potential alternative for or supplement to take along with medication for those who struggle with the symptoms of ADHD. The calming effects of CBD oil could help reduce the unwanted symptoms that so many with ADHD struggle with every day.

 

Sources:

https://www.medicalnewstoday.com/articles/325599.php#can-cbd-oil-treat-adhd

https://www.ncbi.nlm.nih.gov/pubmed/22495620

https://www.additudemag.com/statistics-of-adhd/

https://www.healthline.com/health/adhd/facts-statistics-infographic

https://www.psychiatry.org/patients-families/adhd/what-is-adhd

https://www.ncbi.nlm.nih.gov/pubmed/27227537

https://www.ncbi.nlm.nih.gov/pubmed/21307846

A Simple Guide to CBD Oil

CBD oil has been doing the rounds lately. It has been growing in popularity, and for a good reason:  Its uses are being researched in labs around the world, and more people are making it their business to find out what it actually does.  

You’ve probably heard one or two things yourself and are here to check if what they say is true. Does CBD Oil really help with anxiety disorders? Will it help me sleep better?

We know these questions and more are buzzing around in your head, and in this article, we’ll address all the popular ones. Here’s your beginner’s guide to CBD oil. 

Guide to CBD Oil – What is it? 

First off, CBD is an abbreviation of Cannabidiol, a compound commonly extracted from the Cannabis Sativa L. plant. It is most commonly extracted from the Hemp plant, which is a specific strain of Cannabis that has high CBD content and low THC. 

As you are probably aware, Cannabis is also the plant family that is best known for Marijuana, mainly for its primary psychoactive ingredient – THC (Tetrahydrocannabinol in full). And just like Hemp, it also contains CBD.

However, that’s where the similarity between CBD and THC ends. Unlike THC, CBD has no psychoactive qualities. It does not provide the “high” that is associated with the THC content in Marijuana. 

Apart from this, CBD is usually extracted alongside several other beneficial compounds, including more than 113 minor cannabinoids, terpenes, amino acids, and flavonoids. Together, these compounds have been shown to work beneficially and increase the healing properties of the overall extract. 

So, how is  CBD Oil made? After CBD is extracted from the flowers and leaves of the cannabis plant, it is not easily absorbed into the body alone. To aid chemical absorption, it is usually added to a carrier oil such as coconut or olive oil. Hence CBD Oil. 

Types of CBD oil 

There are three main strains of CBD Oil that you should know. They are:  

Due to the wide variety of therapeutic compounds available in Full-Spectrum CBD oil, it is popular amongst consumers that want all the helpful ingredients they may get. Broad-Spectrum CBD oil and CBD isolate are still a great option, though, especially for people that want to avoid even trace amounts of THC.

What does CBD oil do? 

There are a lot of benefits linked to CBD oil, and these are made possible through the functioning of the endocannabinoid system (ECS). 

Discovered in the 1980s, the ECS is responsible for maintaining homeostasis and balance in the body. Ironically, it was discovered during a big push by President Reagan’s administration to prove that Marijuana caused brain damage.

The ECS maintains homeostasis and balance in the body by regulating the body’s pain response, sleep function, and immune system responses. The body itself produces endocannabinoids on its own, but CBD oil supplements these and enables better functioning of the ECS. 

Due to increased interest in CBD, there are more studies inquiring into the safety of the compound. Several studies already show that CBD is a safe and non-addictive compound with several therapeutic benefits. However, even more, studies now draw clearer conclusions on the health benefits of CBD Oil. These include:  

In addition to these, studies have shown that CBD Oil has a high safety profile and does not possess any significant side effects. The World Health Organization especially found that CBD does not have any abuse or dependence potential, and does not pose any public health-related problems.  

Different ways of taking CBD oil products 

As we have already mentioned in this guide to CBD oil, CBD extract cannot be taken alone. It must be added to a carrier oil to increase its bioavailability (rate of absorption into the body). 

But apart from this, there are many other ways in which CBD oil is applied on or ingested into the body. These include:

Regardless of which of these CBD oil products you prefer, it is always a good idea to pick the product that works best for you, considering your specific needs. 

Conclusion 

Now that you know all about CBD oil and what it may do for you, your next thought is likely to be: where may I get my hands on this stuff? Since the product is available on several online stores, you may get it pretty much anywhere. There are some things you should keep in mind, though:

Are you wondering where to start? You may try out our CBD products. 

With these in mind, you’re well equipped for your first foray into the market for CBD oil products. Enjoyed this guide to CBD Oil? Let us know in the comments section below. 

Sources

https://www.happierhuman.com/guide-cbd-oil/

https://tesseranaturals.com/beginners-guide-to-cbd/

https://cbdoilreview.org/cbd-cannabidiol/cbd-oil-beginners-guide/

How long does CBD stay in your system?

Cannabidiol, better known by its three-letter acronym, CBD, is a compound that may have health benefits for many people. For this reason, many people have started to consume CBD regularly. They may have it before they go to bed, in the morning or in some cases, both. CBD is non-habit forming and non-psychoactive, which means that people may generally consume it to improve overall health.

 

People who use CBD often wonder how long it stays in their systems. To answer this question, let’s first take a look at what CBD is and how the body processes it. From there, we may analyze how long it takes to leave our bodies.

 

What is CBD?

The Cannabis plant family, including Marijuana and Hemp, has chemical compounds called “cannabinoids.” These are chemicals that are unique to the Cannabis plant. There are 113 specific compounds within Cannabis classified as cannabinoids. 

CBD is one of those cannabinoids. Tetrahydrocannabinol (THC), the psychoactive ingredient that evokes a high feeling, is another cannabinoid. There are other substances such as Cannabigerol (CBG), Cannabichromene (CBC), Cannabinol (CBN), etc. that all exist in the plant. 

Each strain of Cannabis and each plant itself has different ratios of these cannabinoids. Most CBD within the United States comes from the Hemp plant. Hemp is, by definition, low in THC. To be legally called Hemp, the THC content must be below 0.3%. However, even though Hemp lacks THC, it’s still rich in other cannabinoids, such as CBD. The CBD you consume comes from the Hemp and not the Marijuana, which makes it legal.

 

Why does CBD affect our bodies?

How CBD and THC produced their effects on our bodies was a mystery until the 1990s when researchers first identified what they called the “endocannabinoid system.” This system gets its name from the prefix “endo,” which means “within” and cannabinoid because the chemicals that bound to are cannabinoids.

The endocannabinoid system was first described as two receptors named CB-1 and CB-2. Our definition of the endocannabinoid system has increased with more research. There are now as many as 70 receptors and enzymes that cannabinoids interact with to exert biological responses.    Each receptor has a different function within our bodies and binds with different cannabinoids. Concentrate on the interactions with CB1 and CB2 to highlight how one molecular can have so many reported effects. For example, CB-1 receptors bind very well with THC but do not link well with CBD. This lack of binding is why THC has the “high” effect that it does, but CBD does not.

CBD affects the CB-2 receptors, which are throughout our entire bodies. They are in our skin, immune cells, heart, blood vessels, and other organs. CB-2 receptors appear to have multiple purposes, including signaling pain and invoking an immune response. 

 

How do our systems process it?

How our body processes CBD depends mostly on how someone uses it. There are three primary ways to take CBD. People either ingest, inhale, or apply CBD topically. Most people elect to take an oral supplement (like CBD oil drops) or use it topically (as in a CBD cream).

For people who ingest CBD orally, their digestive systems first process the compound. It goes into the stomach and then eventually ends up in the liver. The liver breaks down some of the CBD molecules and passes the rest on to the bloodstream.

Some people don’t eat CBD but instead, place a few drops under their tongue. In this case, the membranes in our mouths may transfer this compound to the bloodstream directly, bypassing the liver. If you’re looking to get as much CBD out of the oil as you can, putting it under your tongue is the best way to do that.

Inhaling CBD is another possibility. Much like smoking, when you inhale the compound, it is absorbed through the lungs (the alveoli, to be precise). The CBD molecules wind up on the alveoli and get sent directly to the bloodstream. However, it is important to remember that vaping has been associated with several injuries and some deaths.

With each of these ingestion methods, the CBD chemical reaches the bloodstream. Once CBD is in the blood, your liver takes over. Your liver sorts through all compounds in the blood and works to remove foreign material such as CBD by metabolizing the compound or making chemical modifications to target the molecule for disposal.  The metabolites or chemical modifications of CBD will send these molecules to targeted destinations for removal. From there, your body removes these metabolites via feces and urine. CBD is mostly excreted through feces, with some eliminated through your urine.  

For topical applications, the method of staying in the system is different. Most of the CBD that you apply to a sore knee or a swollen leg never enters the bloodstream. It affects the receptors specifically expressed in the skin, such as localized CB- CB-2 receptors and which provides localized improvements in skin health.

 

How long does CBD oil last in your system?

The question of how long does pure CBD oil last in your system depends partly on how we take it. 

For oral ingestion, there’s evidence that when taken are moderate doses, CBD remains in our systems for 1-2 days. However, there hasn’t been a lot of research on this topic, and due to this, estimates vary. Another study suggested that the half-life of CBD is around 18-32 hours. This statistic means that if you ingest 100 ml of CBD, then within 18-32 hours, you’ll have 50 ml left in your system. Some reports have CBD as remaining in your body for as long as 3-4 days. On average, though, you should expect some CBD to stay in your body for a couple of days, but not much longer.

It’s worth noting that many factors go into how long CBD remains in our systems. For example, CBD is fat-soluble, so our bodies will store it within our fat cells. If you exercise a lot and burn off fat, then you’re more likely to get rid of the CBD particles faster than someone who is sedentary.  Additionally, if you have more body fat, CBD will stay in your body for a longer period of time. With that all said, on average, users may expect to see CBD leaving their body by a couple of days at the most. 

Higher doses of CBD may also have an effect on how long the CBD will stay in the body as opposed to small doses. As with any substance, your liver may only filter so much at once. You may think of your liver as the cleaning service for your blood, and it may break down a certain amount of substances from your blood per hour. As a hypothetical example, suppose your liver may break down 50ml of CBD per hour. If you ingest 600ml, CBD will remain in your system then for 12 hours. However, if you ingest 100ml, CBD will be eliminated in two. Of course, real biological processes are more unpredictable than that. Still, the general premise is the same – taking significant quantities of CBD will mean it stays in your body for longer.

If you take CBD as a lotion, virtually no CBD enters your bloodstream, so it won’t “stay” in your system, per se. Instead, it will remain on the skin layer and may provide your joints some much-needed relief.

 

Why is this information relevant?

Often when people want to know how long CBD remains in their systems, they’re trying to answer one of two questions. Either they want to know how long they may expect to feel the effects, or they want to know how long CBD would be traceable for a drug test.

For the first question, users may typically feel the effects of CBD for 2-6 hours depending on what form of CBD is consumed. Usually, people first start reporting feeling better within 20-30 minutes of ingesting oral CBD. Recall that there are different ways to consume CBD. Those who inhale or vape CBD particles will find that the effects start much quicker (and possibly dissipate faster) than those who take CBD orally. For people who have CBD lotions, they may also expect to feel the effects of these creams for about 5-6 hours. After that, the positive results of CBD diminish.

Some people are worried about taking CBD for fear that it might show up on a drug test. Even though CBD is generally legal, people may be worried that testing positive for CBD would somehow imply that they are smoking Marijuana. After all, both compounds come from the Cannabis family of plants. 

You may be asking: How to get CBD out of your system fast? However, CBD is not typically tested in common drug tests or urinalysis.  Common urine tests monitor whether an individual has consumed intoxicating or controlled substances such as heroin, cocaine, alcohol, or THC. 

Although all hemp products must contain less than 0.3% THC this small amount may trigger a positive response for THC usage.  If you are worried about drug testing, the only products you should consume are CBD isolate or broad spectrum which contains no detectable THC.  Ensure that the company you purchase products from has sufficient quality control to ensure you are not consuming any THC product. Consuming pure CBD products will not result in a positive THC test.

Therefore, how long CBD stays in your system is not likely to have any bearing on drug tests. You may feel free to take CBD in any way you want, and your employer or the state never needs to know.

 

What effects will CBD provide?

Studies regarding the benefits of CBD have generally been reassuring. The FDA cleared CBD for the treatment of epilepsy conditions. Studies have also shown that CBD may help with anxiety, depression, mood stability, and pain relief. Researchers have also posited that CBD may be useful for other conditions as well. Studies have shown it may be able to reduce high blood pressure. Other studies have shown that it may have neuroprotective effects that may help alleviate tremor symptoms in Parkinson’s Disease patients and that it may also benefit heart health.

Much of the research into these CBD effects is ongoing with new results reported daily. What we do know is that the initial body of research has been incredibly promising.

 

Find the right CBD product for you

When it comes to CBD, the key is to find the right product that suits your needs. If you are looking for longer-lasting effects, then an oil might be the best option for you. If you are looking for localized skin health, then the creams are the best option.

While CBD may stay in our systems for as long as 3-4 days, on average, it leaves within a couple of days. You will experience the effects of CBD for approximately 2-6 hours if you ingest it orally. If you apply it topically, you may expect the impact to last around 6 hours and be incredibly localized. CBD creams are a fantastic option for achy joints, whereas CBD oils are better if you want general pain relief or to feel less anxious.

When it comes to how long CBD stays in your system and if it is detectable in a drug test, again, quality matters much more than quantity. CBD brands that focus on quality and purity are much more likely to remain in your body for longer and be less detectable than those with impurities. If you want to experience the benefits that CBD may have for you, look for a high-quality oil or cream and check it out for yourself!

What Does Bioavailability Mean? Does CBD absorb through skin?

Bioavailability has a particularly long and confusing definition that this article narrows down in a more straightforward statement, “the fraction (percentage) of an administered dose of unchanged medicine that reaches the bloodstream (systemic circulation).” Bioavailability relies on the method at which it is delivered. The ways at which Cannabidiol (CBD) is delivered absorbs at different rates. These rates include the time it is taken, the time it has the maximum effect, and does CBD absorb through skin? An example being, an oral CBD product is absorbed through the body at 5-15%. If you take 10 mg of CBD, your body absorbs 0.25mg to 0.75 mgs.

Keep in mind that your dosage will need to increase or decrease depending on your body weight and if the severity of our condition. You may be asking, what does this have to do with a Cannabidiol (CBD) blog? It has everything to do with does CBD absorb through skin?, and we will explain why! CBD products are available with different dosages and applications. We may ask questions such as, how quickly does CBD enter the system? What dosage is right for me? At what point does the body not process the dosage? What is the best way to get CBD into my system? These are the questions that bioavailability may help answer. 

How will this affect my use of CBD & Does CBD absorb through skin?

A chemical that is often aligned with CBD is THC (tetrahydrocannabinol). There have been a few studies done on the detection of THC in the body. This document states, “The number, duration, and spacing of puffs, hold time, and inhalation volume, or smoking topography, greatly influences the degree of drug exposure.” How can we interpret this to the use of a does CBD absorb through skin? First, we must understand the difference between THC and CBD. THC and CBD are found in the cannabis plant. THC has been spoken about more frequently in years before. The brother/sister of THC is CBD. CBD is found in the cannabis plant but is also found in the hemp plant. THC is the psychoactive element that someone can get “high” from. Our article explains the difference between the two in detail, explaining that CBD is of a non-psychoactive nature and is now becoming more looked upon in a therapeutic way to perhaps help with the relief of certain things. With this information, we can now understand that although the effects are different and may be used in different ways, the way that THC and CBD are handled in a user’s body are the same. 

Depending on who you are, and your use of CBD absorb through skin?, the effectiveness you’ll receive will be different. This study used cannabidiol to test an anti-inflammatory effect. It states that after applying the CBD to the abdomen of the mice for 72 hours, a steady state level continued until 24 hours and continued to last until the end of the experiment at the seventy two hours. The study’s conclusion being that the application to the mice’s abdomen improved inflammation and edema caused by the injection. To summarize, CBD in this study reached a peak concentration at twenty four hours with effects lasting through seventy two hours. What does this mean for users of CBD? 

Open Wide

In far more simple terms, users of CBD can change the strength of CBD, or type of manufactured CBD product to increase or decrease the amount of CBD that enters your body. Using CBD orally by using gummies, drinks, or soft gels means that you’ll be getting the effects more slowly than via the absorption under your tongue by using tinctures, providing a longer onset and longer duration of effects. The digestive process may prolong the effects CBD may have on users. Our bodies are all different shapes and sizes; therefore, we digest food/medication in different time frames. Once the gummy, pill or drink has entered your gastrointestinal tract, it must survive degradation by stomach acid then be absorbed in your small intestine.  The CBD then passes through the liver and on to the bloodstream. A CBD user’s bioavailability orally may depend on age, height, weight, the time of day the CBD was taken orally, genetic make up for liver metabolizing enzymes, the physical activity level, the content of the stomach, level of stress, and sex of the person. Three well-defined studies have evaluated the bioavailability in CBD oral capsules.  Overall, these studies show that the maximum concentration of CBD is achieved between 1 and 3 hours. These studies demonstrate the CBD bioavailability in different people. Additionally, when subjects had food in their system, there was an observed delay in reaching peak CBD concentrations. The effect of taking CBD oral capsules with food should be considered. If you wish to feel effects faster, perhaps take your oral CBD, whether this is a gummy, drink or soft gel capsule on an empty stomach.   

Under the tongue

While the surface under the tongue absorbs the CBD far more quickly into the bloodstream, therefore your bioavailability is higher. This study tested rabbits with solid CBD and a CBD under the tongue. They found that the CBD administered under the tongue enhanced the rate at which the CBD entered the bloodstream. What CBD can be placed under the tongue? Pure CBD oil, tinctures and liquids. This may be used in the morning, evening or during the day. Be sure to read the recommended dose when first beginning. Our Panacea Pure CBD Oil Drops are administered orally for the above effects and the bioavailability may be higher than the other options if you want to feel the effects the CBD may have more quickly. 

On the skin 

Does CBD absorb through skin? In the topical form such as, salves, balms, and lotions have a far lower bioavailability than tinctures and gummies, etc.  According to this article, generally, the skin has low permeability (this means skin does not allow much through it easily) and blocks things from passing through the skin into your body. The skin has a low rate of absorption for cannabinoids because of this permeability function. CBD salves, balms and lotions, therefore, need to have high concentrations of CBD or mixed with a skin permeability agent such as menthol to be absorbed properly. With permeability in mind, CBD topicals need to be applied liberally into the skin for it to sink in through the pores properly. This information tells users that because the absorption of CBD in the skin is lower than, for example, through the area under your tongue, the amount of time it takes to absorb through the skin will be slower.  Because topical application has low bioavailability, CBD applied to the skin will target local skin cells and nerve endings in the skin for local effects.   

Vape

Vaping has recently been a very popular method of dosing CBD or THC.  While vaping cannabinoids provides high bioavailability and rapid onset, the effects of CBD is relatively short and has numerous reported side effects. Panacea Life does not advocate vaping CBD. When CBD is inhaled, it is absorbed through the alveoli (tiny air sacs) in your lungs. The human lungs are covered in these alveoli and therefore have a larger surface area to be absorbed. This article states, “Once through the alveoli, the CBD molecules are immediately transferred into the bloodstream. Recent reports indicate that there are many negative health effects presented by vaping.  We state in another post that we invite our customers to try all options of adding CBD into your daily life via your diet. Examples being soft gels, tinctures, gummies or vaping. Panacea wants to give you the knowledge to make the best choice for you. Panacea Life, however, does not encourage the method of vaping. 

What about my pet? 

First, always speak to a veterinarian before giving your furry friend CBD as it may not be right for them. The bioavailability, according to this study, does not particularly correlate with that of the human bioavailability. Therefore, speaking with your veterinarian before giving your pet any type of CBD should be of the utmost importance. You can find more information on CBD for your pet here. We offer CBD tincture and soft gels for your pet. Make sure to follow the directions to allow your animal to feel the proper effects without feeling uncomfortable. The most important looking for CBD for pets is to find a product with no traces of THC. 

Overall.

Bioavailability is different for each person and it directly correlates with the type of CBD one may use. If you’re the type of person who wants the effects as quickly as possible, finding oil to place under your tongue that is right for you is the way to go. Or if you prefer a slower effect or you’re not in any rush, oral CBD may be right for you. CBD has the best results when used the same way every time and when it becomes a habit. Keep this in mind when choosing the CBD right for you. CBD affects everyone differently. So you may be open for a bit of trial and error on what may be needed to get the effects you want. Start small, and see what feels the best for you.   

Sources:

https://eupati.eu/pharmaceutical-development/bioavailability-and-bioequivalence/ 

https://www.sciencedirect.com/science/article/pii/S0168365903004152

https://www.tandfonline.com/doi/abs/10.1300/J175v01n03_12

https://ocrc.net/how-does-the-body-metabolize-medication/

https://link.springer.com/article/10.1007/s00228-012-1393-4

https://www.ncbi.nlm.nih.gov/pubmed/17051591

https://echoconnection.org/cbd-absorbed-body/

Could (Cannabidiol) CBD help Parkinson’s?

There are an estimated 10 million people around the world who have Parkinson’s Disease, which may be under-represented due to misdiagnosis or not diagnosing the condition at all. The Center for Disease Control puts complications connected with the disorder as the 14th main cause of death in America.

The symptoms of Parkinson’s Disease may make daily functions difficult for those who suffer from the disease. This often leaves them looking for ways to manage daily life. Medical research from the last few decades suggests that CBD oil has the potential to lessen symptoms.  

 

What is Parkinson’s Disease?

Parkinson’s Disease (PD) is a disorder that affects the nervous system. Symptoms include motor skill impairment, often making basic daily functions much more difficult. Parkinson’s Disease usually presents slowly with symptoms often starting as a slight shake or stiffness in one hand. However, since this is a progressive disease, symptoms get increasingly worse as time goes on.

Parkinson’s has five stages of disease progression from mild to severe. Most people may maintain independence throughout most until stages four and five when the condition becomes debilitating.

As mentioned, Parkinson’s Disease symptoms impair motor function, which will change how the body moves.  For example, patients may stop moving their arms when they walk, or writing may become more difficult, affecting balance, even altering facial expressions. Parkinson’s Disease may also cause issues with functions that are not necessarily related to motor skills, including speaking, swallowing, and a diminishing sense of smell.

Many of the issues faced by those who have Parkinson’s Disease are caused by the body failing to produce a compound called dopamine. This compound helps regulate movement. Without it, motor functions become more difficult, often affecting the body in more ways than one would originally think.

It is not clear what exactly causes Parkinson’s Disease. There is evidence that suggests that there are potential genetic causes. Some research also indicates that there may be environmental causes. Constant exposure to certain chemicals might increase risk. Head injuries may also be a cause of Parkinson’s Disease.  

There are about one million people in the United States alone who currently suffer from the disease. Most of these people are over the age of 50, but it has been known to affect younger people as well. Parkinson’s Disease is twice as common in men.

The impairment of motor function causes patients to struggle with every day tasks.  As a result, these patients are seeking various ways to cope, including adding dietary supplements.  One possible supplement to alleviate symptoms is CBD.  

Many still don’t know what CBD is or what it may do.

 

What is CBD?

Cannabidiol usually referred to as CBD, is a compound found in Hemp and Marijuana, plants that are members of the Cannabis family. CBD has recently been explored by many people to provide a wide range of health benefits, including mental well-being.   

Unlike it’s more well-known cousin THC (tetrahydrocannabinol), CBD does not provide a high. Most users do report a feeling of calm or relaxation, but CBD doesn’t have the same psychoactive effect that is normally associated with Cannabis. 

One major difference between CBD and THC is the type of plant that product manufacturers obtain these cannabinoids from.  CBD manufacturers most often derive CBD from hemp. Hemp-derived CBD is legal in all 50 states, where Marijuana derived-anything has yet to be legalized across the United States. Hemp also has much higher levels of CBD than THC. Marijuana, on the other hand, has higher concentrations of THC. 

Another difference between them is how the two cannabinoids interact with the body’s endocannabinoid system, a series of receptors and enzymes that regulate many of the body’s cognitive functions. THC binds directly with the two most common Endocannabinoid receptors, CB1 and CB2. This causes a change in the body’s ability to regulate functions like memory and appetite. This is why the traditional “stoner” is often portrayed in pop culture as forgetful and constantly hungry.

CBD, on the other hand, does not directly bind with these receptors. Instead, CBD interacts with a different set of receptors modulating many different brain and body functions. In doing this, CBD does not provide a high, but the receptors it stimulates may increase pain tolerance or may boost your mood. This is because these receptors often regulate things like the production of serotonin and, what could be a benefit for those who suffer from Parkinson’s disease, dopamine.

 

How CBD may help Parkinson’s Disease

Marijuana, whether medical or recreational, is not federally legal in the United States, and several states have not legalized it. This doesn’t mean that Cannabis is completely inaccessible to those who don’t live in states with legal, medical Marijuana. In fact, Hemp is legal in all 50 states, making Hemp-derived CBD legal across the country.

But may CBD provide any help for those with Parkinson’s disease? Findings from research suggest CBD has great potential to modulate Parkinson’s symptoms.  

Most of the studies done on how CBD interacts with Parkinson’s Disease have been focused on specific symptoms. These studies range from looking at how CBD may help those with the disease sleep to how it may help with Parkinson’s Disease caused psychosis. 

RBD (REM sleep behavior disorder) is another symptom of Parkinson’s Disease that is a bit less known. RBD causes muscle weakness during sleep that is also associated with movement in sleep and nightmares. RBD may make sleeping very difficult for those with Parkinson’s Disease. A study published in 2014 looked at how CBD may help combat this symptom, potentially leading to better sleep for Parkinson’s Disease patients. It was a smaller study, consisting of giving CBD to four people with Parkinson’s Disease. Each of those four patients saw near-immediate and substantial improvement in their RBD.   This could possibly mean that CBD may help Parkinson’s Disease patients have better sleep quality.

Psychosis is another Parkinson’s symptom that tends to appear during the later stages of the disease. The psychosis presents as delirium and hallucinations. In 2009 a small study was done to look at how CBD could help calm this particularly debilitating symptom. Six people with Parkinson’s Disease and Parkinson’s Disease-caused psychosis were selected and prescribed 150 mg of CBD a day. After four weeks of use, the test subjects showed a significant drop in their psychosis symptoms. Despite the size of this study, it is still very promising (Links below).

The most well-known symptom of Parkinson’s Disease is tremors. Tremors are rhythmic shaking that mainly affects the hands but may cause problems throughout the whole body. One study looked to see if CBD may help reduce these tremors finding that CBD may help reduce tremors, steadying the hands.

One study, published in 2014, tested the overall quality of life of people with Parkinson’s Disease when using CBD. Out of the three test groups, those who were taking the highest concentration of CBD daily (300 mg, as opposed to 75 mg and placebo) reported having a better quality of life and an improved sense of well-being.

Parkinson’s Disease, like many other chronic illnesses, may cause problems with someone’s mental health. One common symptom is anxiety—most people who use CBD for reducing mental stress point to the compound’s calming effect. The calming effect of CBD may help keep Parkinson’s Disease caused anxiety under control.

There have been many promising studies that have looked at how CBD affects inflammation. Many of these studies have suggested that CBD could help decrease inflammation helping increase movement and flexibility. The anti-inflammatory effects of CBD may help Parkinson’s patients, as well.   

It would appear that CBD’s ability to stimulate the production of dopamine has the potential to help with symptoms of Parkinson’s Disease. The question now is, how do you take it?

 

How to take CBD

CBD comes in many different forms, strains, and concentrations. That means that there are many different ways that you could take CBD. One of the more common ways in orally. This is usually through products like tinctures, tablets, and edibles.

There are also CBD topicals, like lotions, that may be great options for symptoms like joint inflammation. However, topical application is not necessarily the best way to get the full benefits of CBD. As detailed above, most of the studies done on how CBD may help with Parkinson’s Disease have given CBD to the test subjects orally. This may suggest that taking CBD by mouth may be the best way to get the potential benefits for Parkinson’s Disease. 

There are also different kinds of CBD that go beyond strains and concentrations. They are referred to as spectrums. There are three different kinds of CBD spectrums: Full-Spectrum, Broad-Spectrum, and CBD isolate. There are multiple other cannabinoids that come from the same part of the plant as CBD. When CBD is extracted, other compounds are extracted with the CBD. The names of the different spectrums reference how many other compounds are in the product beyond CBD. 

Full-Spectrum is the least processed. It is CBD oil with everything else that comes with it, including THC and terpenes (which are cannabinoids that give Cannabis plants their flavor and smell). Broad-spectrum is the in-between of Full-Spectrum and CBD Isolate. It has everything that comes with CBD, except the THC. This, and Full-Spectrum, are likely to have more potent effects since it is common for the compounds to build on each other to create a stronger reaction. On the far end of the list of spectrums, there is CBD Isolate. It is the most processed version, consisting of just CBD and nothing else.

When first taking CBD, it is best to start the dosage as small, bottles you purchase should show a serving size and amount of CBD in milligrams concentrated in a serving. Try the milder strains at low concentrations. If these seem to be helping, without unpleasant side effects, you may try upping your dose. It is important to bear in mind that everyone will experience CBD differently. One strain that is does nothing for someone may be too strong for someone else. Be ready to experiment and try different kinds of CBD products.

CBD will not cure your Parkinson’s. However, others have observed that it may help regulate the symptoms. Be sure to talk to your doctor before you start using any CBD product. There aren’t any serious side effects associated with CBD (the side effects that are associated with it mainly consist of things like mild nausea, fatigue, and dry mouth). Usually, the side effects are also mainly felt by those who use CBD at very high concentrations. However, it may not interact well with medications you may be on. There also is no information as to how it may affect Parkinson’s patients long-term as research to evaluate long-term benefits has not yet been conducted.

Parkinson’s disease may be hard to live with. However, there are ways to help regulate the symptoms, making the disorder more tolerable. Research is showing that CBD may be a potential way to do that.

 

Source:

https://www.ncbi.nlm.nih.gov/pubmed/25237116

https://www.ncbi.nlm.nih.gov/pubmed/21545415

https://www.ncbi.nlm.nih.gov/pubmed/17196181

https://www.ncbi.nlm.nih.gov/pubmed?term=cannabidiol%20can%20improve%20complex%20sleep%20related%20behaviors%20associated%20with%20rapid%20eye%20movement%20sleep%20behaviour%20disorder%20in%20parkinson%27s%20disease%20patients%20a%20case%20series&cmd=correctspelling

https://www.ncbi.nlm.nih.gov/pubmed/18801821

https://www.ncbi.nlm.nih.gov/pubmed/3793381

https://www.healthline.com/health/parkinsons-disease/cbd-oil-for-parkinsons#treating-parkinsons

https://www.dementiacarecentral.com/parkinsons/treating/cbd/

https://www.apdaparkinson.org/what-is-parkinsons/

https://www.healthline.com/health/parkinsons#symptoms

https://www.parkinson.org/understanding-parkinsons/what-is-parkinsons

https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055